Table 5.

Results of multivariate analyses showing variables associated with higher risk of ESRD

VariableNot Age AdjustedAge Adjusted
Hazard Ratio (95% Confidence Interval)P ValueHazard Ratio (95% Confidence Interval)P Value
Age >65 yrNot included0.41 (0.27 to 0.62)<0.001
eGFR (ml/min per 1.73 m2)
 >30 ReferentReferent
 15–302.38 (1.45 to 3.91)<0.0012.58 (1.58 to 4.21)<0.001
 <154.35 (2.29 to 8.28)<0.0014.52 (2.38 to 8.56)<0.001
PCr>30 mg/mmol1.96 (1.20 to 3.12)0.011.77 (1.10 to 2.84)0.01
Phosphate >4.65 mg/dl1.70 (0.98 to 2.96)0.061.70 (1.0 to 2.95)0.05
cFLC (mg/L)
 Quartile 1/2: <68.9ReferentReferent
 Quartile 3: 68.9–100.71.60 (0.92 to 2.76)0.091.72 (1.0 to 2.97)0.05
 Quartile 4: >100.73.37 (2.00 to 5.70)<0.0013.73 (2.10 to 6.30)<0.001
  • When protein-to-creatine ratio (PCr) not available, estimated from 24-h urinary protein on the basis of the assumption that a PCr of 100 mg/mmol is approximately 1 g per 24-h proteinuria. cFLC, combined free light chain.