Table 4.

Results of multivariate analyses showing variables associated with higher risk of mortality

VariableNot Age AdjustedAge Adjusted
Hazard Ratio (95% Confidence Interval)P ValueHazard Ratio (95% Confidence Interval)P Value
Age >65 yrNot included4.01 (2.95 to 5.45)<0.001
eGFR (ml/min per 1.73 m2)
 >30 ReferentReferent
 15–301.45 (1.10 to 1.91)0.011.37 (1.04 to 1.80)0.02
 <151.16 (0.75 to 1.78)0.511.27 (0.82 to 1.96)0.27
CVD2.61 (2.05 to 3.32)<0.0011.82 (1.41 to 2.33)<0.001
cFLC (mg/L)
 Quartile 1: <49.4ReferentReferent
 Quartile 2: 49.4–68.80.87 (0.57 to 1.30)0.481.18 (0.57 to 1.27)0.42
 Quartile 3: 68.9–100.71.51 (1.03 to 2.21)0.031.49 (1.02 to 2.18)0.04
 Quartile 4: >100.71.97 (1.33 to 2.92)<0.0011.99 (1.34 to 2.93)<0.001
  • CVD, cardiovascular disease; cFLC, combined free light chain.