Table 4.

Unadjusted and adjusted relative hazard for each 1-point increase in the CFS score including sensitivity analysis

ModelN/EventsHazard Ratio95% Confidence IntervalP Value
Primary analyses
 Unadjusted390/961.421.25 to 1.61<0.001
 Model 1a390/961.321.15 to 1.52<0.001
 Model 2b 390/961.301.12 to 1.51<0.001
 Model 3c390/961.221.04 to 1.430.02
 Model 4d372/901.211.02 to 1.430.03
Sensitivity analyses
 Model 5e390/991.211.03 to 1.420.02
 Model 6f378/921.231.04 to 1.450.02
 Model 7g390/441.250.99 to 1.580.06
  • CFS, Clinical Frailty Scale.

  • a Adjusted for age, race, and sex.

  • b Adjusted for age, race, sex, Charlson Comorbidity Index ≥5, and diabetic ESRD.

  • c Adjusted for age, race, sex, Charlson Comorbidity Index ≥5, diabetic ESRD, GFR (Modification of Diet in Renal Disease formula), albumin, dialysis modality, and location of dialysis start.

  • d Adjusted for age, race, sex, Charlson Comorbidity Index ≥5, diabetic ESRD, GFR (Modification of Diet in Renal Disease formula), albumin, dialysis modality, location of dialysis start, and body mass index.

  • e Model 3 including survival time after transplantation.

  • f Model 3 excluding failed kidney allografts.

  • g Model 3 restricted to mortality within the first 1 year.