Table 3.

Demographic, clinical, and hemodynamic characteristics of study participants according to the tertile of ambulatory augmentation index during the dialysis-off day

VariableHigh Tertile (24-hr AIx >32.3%)Medium Tertile (24-hr AIx 24.1%–32.3%)Low Tertile (24-hr AIx <24.1%)P Value
Patients (n)515151
24-hr AIx (%)39.6±5.128.4±2.517.7±4.4<0.001
Age (yr)69.6±11.764.5±13.356.9±15.2<0.001
Sex, n (%)
 Female33 (64.7)21 (41.1)10 (19.6)<0.001
 Male18 (35.3)30 (58.9)41 (80.4)
Body weight (kg)69.2±12.871.7±13.879.4±15.90.001
Height (m)1.64±0.11.66±0.21.71±0.10.20
Body mass index (kg/m2)25.8±5.226.9±5.427.0±4.80.74
Presence of diabetes, n (%)26 (50.9)15 (29.4)10 (19.6)<0.001
Presence of hypertension, n (%)43 (84.3)40 (78.4)39 (76.4)0.54
Presence of dyslipidemia, n (%)14 (27.4)16 (31.4)11 (21.5)0.58
Smoking, n (%)12 (23.5)11 (21.5)11 (21.5)0.55
History of coronary heart disease, n (%)16 (31.3)11 (21.5)8 (15.6)0.12
History of cerebrovascular disease, n (%)5 (9.8)5 (9.8)4 (7.8)0.78
Dialysis vintage (mo)38.2±5.736.7±5.141.2±5.20.78
Interdialytic weight gain (kg)1.2±0.52.1±0.92.0±1.00.21
Primary cause of ESRD, n (%)
 Diabetic kidney disease20 (39.3)11 (21.6)7 (13.7)<0.001
 Hypertension5 (9.8)4 (7.8)4 (7.8)
  GN6 (11.7)8 (15.8)12 (23.5)
 Obstructive nephropathy4 (7.8)4 (7.8)2 (3.9)
 Polycystic kidney disease1 (1.9)1 (1.9)4 (7.8)
 Unknown nephropathy15 (29.5)23 (45.1)22 (43.3)
24-hr mean BP (mmHg)107.2±12.6103.1±11.7100.5±12.60.02
24-hr brachial SBP (mmHg)141.9±17.2131.6±15.0127.1±16.2<0.001
24-hr brachial DBP (mmHg)77.9±10.878.9±10.778.1±11.10.86
24-hr brachial PP (mmHg)64.0±12.752.7±10.749.0±10.8<0.001
24-hr aortic SBP (mmHg)127.3±15.1120.7±14.4117.1±14.3<0.001
24-hr aortic DBP (mmHg)79.4±11.180.5±10.779.6±11.30.88
24-hr aortic PP (mmHg)47.9±10.040.2±8.837.5±7.3<0.001
24-hr heart rate (beats/min)66.8±7.474.0±7.679.8±8.9<0.001
24-hr PWV (m/sec)10.4±1.89.4±2.48.3±2.1<0.001
  • Data are presented as mean ± SD or absolute and relevant frequencies.