Table 1.

Staged diagnostic criteria for AKI

Definition and Criteria for AKI StagesModifications
pRIFLE
 Stage 1 (Risk): eGFR decreased by 25%
 Stage 2 (Injury): eGFR decreased by 50%
 Stage 3 (Failure): eGFR decrease by 75%
or
 eGFR <35 ml/min per 1.73 m2
AKIN
 Stage 1: Increase in creatinine of ≥50%0.3-mg/dl increase added to stage 1
orAKI diagnosed over 48-hr period
 Absolute increase in creatinine of 0.3 mg/dl
 Stage 2: Increase in creatinine of ≥100%
 Stage 3: Increase in creatinine of ≥200%
KDIGO
 Stage 1: Increase in creatinine of ≥50%eGFR threshold from pRIFLE added to stage 3
orCreatinine changes (except absolute 0.3-mg/dl increase) required to occur within a 7-d time frame
 Absolute increase in creatinine of 0.3 mg/dl
 Stage 2: Increase in creatinine of ≥100%
 Stage 3: Increase in creatinine of ≥200%
or
 eGFR ≤35 ml/min per 1.73 m2 (if age <18 yr)
  • eGFR was estimated using the Schwartz method. pRIFLE, pediatric RIFLE; AKIN, Acute Kidney Injury Network; KDIGO, Kidney Diseases Improving Global Outcomes.