Table 4.

Independent predictors of upper gastrointestinal bleeding(defined by stringent criterion) after dialysis-requiring AKI

VariableHazard Ratio (95% Confidence Interval)P Value
Age (per decade)1.20 (1.15 to 1.25)<0.001
AKI-recovery groupa1.30 (1.14 to 1.48)<0.001
Premorbid moderate/severe liver disease1.57 (1.25 to 1.95)<0.001
Acute hepatic dysfunction1.59 (1.10 to 2.29)0.01
Severe sepsis1.29 (1.08 to 1.54)0.01
Long-term use of corticosteroids1.28 (1.01 to 1.62)0.04
NSAIDs1.58 (1.32 to 1.89)<0.001
Aspirin1.71 (1.36 to 2.14)<0.001
Time-varyingb CKD1.83 (1.53 to 2.20)<0.001
Time-varyingb advanced CKD2.10 (1.31 to 3.36)0.002
Time-varyingb ESRD2.31 (1.92 to 2.79)<0.001
  • a In contrast to non-AKI group.

  • b “Time-varying” denotes some time during follow-up.