Table 2.

Characteristics at initiation of RRT (n=1,557,117), end-stage lupus nephritis

VariableESLN (%)Logistic Regression
Yes (n=16,650)No (n=1,540,467)ReferenceAOR for ESLN (95% CI)
Year of first RRT
 1995–200034.131.32001–20050.97 (0.93 to 1.01)
 2001–200532.932.62001–20051 (Reference)
 2006–20103336.12001–20050.94 (0.9 to 0.98)
Age
 <20 yr6.71.2<201 (Reference)
 20–29 yr22.82.5<201.46 (1.36 to 1.57)
 30–44 yr35.110.5<200.56 (0.52 to 0.6)
 45–64 yr27.936.6<200.12 (0.12 to 0.13)
 ≥65 yr7.649.3<200.03 (0.02 to 0.03)
Female81.744.8Male6.13 (5.89 to 6.38)
Race/ethnicity
 White43.465.5White1 (Reference)
 African American48.628.5White1.88 (1.81 to 1.95)
 Other86White1.43 (1.34 to 1.52)
 Hispanic 17.212.9Non-Hispanic1.43 (1.37 to 1.5)
Ischemic heart disease6.224.3Absent0.63 (0.59 to 0.67)
Peripheral vascular disease3.214.1Absent0.47 (0.43 to 0.51)
Cerebrovascular disease5.19.2Absent1.06 (0.99 to 1.14)
Diabetes8.850.2Absent0.12 (0.12 to 0.13)
Smoking3.95.6Absent0.67 (0.62 to 0.72)
Alcohol abuse0.51.5Absent0.39 (0.31 to 0.48)
Drug abuse0.81.1Absent0.34 (0.28 to 0.4)
Initial mode of RRT
 Hemodialysis85.790.5Hemodialysis1 (Reference)
 Peritoneal dialysis11.57.8Hemodialysis0.96 (0.91 to 1.01)
Transplant2.81.7Hemodialysis0.8 (0.73 to 0.88)
Initial hemodialysis access
 Fistula7.813.9Fistula1 (Reference)
 Graft2.83.6Fistula1.04 (0.86 to 1.26)
 Catheter89.482.5Fistula1.29 (1.16 to 1.42)
Nephrology care≤ 12 mo68.575.8>120.59 (0.56 to 0.62)
eGFR>15 ml/min per 1.73 m210.710.3b≤151.26 (1.19 to 1.32)
Body mass index≥ 30 kg/m222.430.5<300.53 (0.51 to 0.55)
Serum albumin< 3.5 g/dl7364.7≥3.51.46 (1.4 to 1.52)
Serum hemoglobin≥ 9 g/dl58.171.3<90.87 (0.84 to 0.9)
  • Parameter estimates are presented as column percentages or odds ratios with 95% CIs in parentheses. For logistic regression, all variables in the first column were used as candidate variables, while age, sex, race, and ethnicity were used as adjustment variables, provided they were not also the candidate variable, in which case they were removed as adjustment variables. Data fields for predialysis vascular access for hemodialysis and predialysis nephrology care were available only in the 2005 version of the Medical Evidence Report. Missing data were as follows: initial hemodialysis access, 63.3%; prior nephrology care, 59.4%; eGFR, 1.5%; body mass index, 4.7%; serum albumin, 25.2%; serum hemoglobin, 11.1%. ESLN, end-stage lupus nephritis; AOR, adjusted (for age, sex, race, ethnicity) odds ratio.