Table 2.

Baseline characteristics of the patients according to quartiles of surfactant protein B (HDL)

CharacteristicQuartile 1 (n=288)Quartile 2 (n=288)Quartile 3 (n=288)Quartile 4 (n=288)P Value
SP-B(HDL)1.66 (1.36)4.92 (0.91)9.19 (1.75)22.98 (10.11)
SAA(HDL)6.25 (5.90)8.43 (7.83)9.11 (7.82)10.74 (8.76)<0.001
Age, yr63.8 (8.3)65.8 (8.2)67.3 (8.0)68.3 (7.9)<0.001
Body mass index, kg/m228.5 (5.2)28.0 (4.7)27.0 (4.5)26.7 (4.5)<0.001
Sex (men), %163 (57)160 (56)157 (55)148 (51)0.62
Nonsmoker, n (%)176 (61)176 (61)176 (61)160 (56)0.49
History, n (%)
 Arrhythmia50 (17)39 (14)59 (20)64 (22)0.04
 Coronary artery disease71 (25)79 (27)93 (32)100 (35)0.04
 Congestive heart failure82 (28)90 (31)121 (42)119 (41)<0.001
 Transitory ischemic attack49 (17)59 (20)48 (17)48 (17)0.56
Systolic BP, mmHg145 (22)146 (22)147 (22)145 (22)0.59
Diastolic BP, mmHg75 (10)76 (11)77 (12)75 (11)0.62
Total cholesterol, mg/dl228.9 (43.6)222.1 (42.0)214.0 (39.4)212.6 (41.5)<0.001
LDL cholesterol, mg/dl126 (30)127 (30)126 (27)124 (30)0.70
HDL cholesterol, mg/dl36 (15)35 (11)36 (12)39 (15)<0.01
Apolipoprotein A-I, mg/dl127.8 (24.5)126.5 (22.3)124.6 (23.5)126.0 (24.4)0.45
Triglycerides, mg/dl267.0 [239.0]238.5 [185.0]203.0 [150.0]185.0 [131.5]<0.001
Phosphate, mg/L6.3 (1.5)6.1 (1.5)5.8 (1.6)6.0 (1.8)0.002
C-reactive protein, mg/L5.9 [8.8]5.9 [8.6]6.0 [8.3]7.0 [9.3]0.68
Albumin, g/dl3.9 (0.3)3.8 (0.3)3.8 (0.3)3.8 (0.3)<0.001
Hemoglobin, g/dl10.9 (1.3)11.0 (1.4)10.9 (1.3)10.8 (1.3)0.21
HbA1c, %6.9 (1.2)6.7 (1.2)6.7 (1.3)6.6 (1.2)0.06
  • Data shown are means (SDs) or medians [interquartile ranges] if not otherwise mentioned. P values for comparison of groups were derived from ANOVA models (for continuous variables) or logistic regression models (for categorical variables).