Table 2.

Baseline clinical and biologic data of enrolled subjects

Clinical and Biological DataEndemic Villages (n=1687)Control Nonendemic Villages (n=372)Bosnian Immigrantsa (n=102)P value
Age, yr50 (18–91)53 (18–90)b52 (20–86)0.02
Sex (men), %40.440.937.30.80
Living in village, yr41 (24–55)45 (26–60)18 (15–21)b,c<0.001
Family history of EN (positive), %37.21.1b2.0b<0.001
Height, cm168 (161–175)167 (160–175)167 (160–174)0.40
Weight, kg76 (66–88)79 (68–89)74 (64–87)0.09
Body mass index, kg/m226.87 (23.71–30.74)27.66 (24.30–31.25)26.59 (23.81–29.91)0.07
Systolic BP, mmHg135 (120–154)138 (123.5–159.8)137 (126–156)0.07
Diastolic BP, mmHg81 (75–90)81 (75–92)82 (76–90)0.77
Hypertension, %41.244.643.80.48
Diabetes, %6.19.27.90.09
CKD, %16.69.16.9<0.001
  • a Bosnian immigrants who settled in the EN area 15–30 years ago. Values are expressed as medians and interquartile ranges (25th–75th; minimum to maximum for age) or percentage if indicated.

  • b Significant difference (P<0.05) with endemic villages group.

  • c Significant difference (P<0.05) with control nonendemic villages group.