Table 2.

Characteristics of study population by baseline troponin T concentration (n=3752)

CharacteristicTroponin T Quartiles
≤2.99 (Below Limit of Detection)3.00–5.575.58–10.58>10.58
Number of participants1336671926819
Demographics
 Age (yr) (SD)70 (4)72 (5)73 (5)75 (6)
 Women, n (%)1050 (79)463 (69)515 (56)323 (39)
 Black race, n (%)248 (19)94 (14)143 (15)172 (21)
Prevalent cardiovascular disease, n (%)
 History of coronary heart disease161 (12)103 (15)192 (21)223 (27)
 History of stroke20 (2)17 (3)34 (4)63 (8)
 History of cardiovascular disease177 (13)116 (17)220 (24)264 (32)
 Left ventricular hypertrophy (electrocardiogram Cornell volt)40 (3)30 (5)54 (6)75 (9)
Cardiovascular disease risk factors
 Hypertension, n (%)689 (52)368 (55)623 (67)574 (70)
 Systolic BP (mmHg) (SD)133 (20)135 (20)140 (22)142 (23)
 Diastolic BP (mmHg) (SD)70 (11)70 (11)72 (12)72 (12)
 Hypertension medications, n (%)531 (40)286 (43)485 (52)474 (58)
 ACE inhibitors, n (%)67 (5)42 (6)73 (8)69 (8)
 Diuretics, n (%)310 (23)161 (24)274 (30)303 (37)
 Diabetes, n (%)151 (11)100 (15)172 (19)231 (28)
 Smoking, n (%)
  Never634 (48)331 (50)450 (49)369 (45)
  Former512 (38)273 (41)386 (42)362 (44)
  Current189 (14)65 (10)89 (10)88 (11)
 Body mass index (kg/m2) (SD)26.7 (4.7)26.5 (4.9)27.0 (4.9)26.8 (4.6)
 Total cholesterol (mg/dl) (SD)219 (38)215 (37)211 (38)204 (41)
 LDL cholesterol (mg/dl) (SD)134 (36)132 (34)130 (35)125 (35)
 HDL cholesterol (mg/dl) (SD)58 (16)55 (16)54 (16)51 (16)
 Triglycerides (mg/dl), median [interquartile range]120 [93–164]120 [91–163]120 [91–164]121 [93–166]
 Troponin (pg/ml), median [interquartile range]80 [44–142]94 [51–182]127 [66–247]207 [98–469]
Kidney function
 eGFRa (ml/min per 1.73 m2) (SD)78 (16)75 (17)71 (17)60 (20)
 Cystatin C (mg/L) (SD)0.95 (0.18)0.99 (0.22)1.04 (0.22)1.26 (0.55)
  • a eGFR cystatin C (Chronic Kidney Disease Epidemiology Collaboration). ACE, angiotensin converting enzyme.