Table 3.

Parameters depending on the reduction in 24-hour urine sodium content between weeks 8 and 16

VariablesInteraction P ValueWeek 8Week 16P Value (16 Versus 8)
Intensive education
 24-h Urine albumin (mg/d)a<0.001
  8th–16th 24-h Na reduction<25% (n=60)259.0±1.1212.4±1.10.02
  8th–16th 24-h Na reduction>25% (n=58)319.9±1.1161.5±1.1<0.001
 24-h Urine Na+ (mEq/d)<0.001
  8th–16th 24-h Na reduction<25% (n=60)125.9±7.3139.1±5.90.01
  8th–16th 24-h Na reduction>25% (n=58)190.3±7.3103.8±6.0<0.001
 Systolic BP (mmHg)0.89
  8th–16th 24-h Na reduction<25% (n=60)123.2±1.7121.5±1.90.36
  8th–16th 24-h Na reduction>25% (n=58)121.9±1.8120.6±1.90.49
 Diastolic BP (mmHg)0.54
  8th–16th 24-h Na reduction<25% (n=60)73.7±1.373.9±1.30.91
  8th–16th 24-h Na reduction>25% (n=58)74.2±1.373.3±1.40.46
Conventional education
 24-h Urine albumin (mg/d)a0.03
  8th–16th 24-h Na reduction<25% (n=60)241.9±1.1234.4±1.10.66
  8th–16th 24-h Na reduction>25% (n=58)276.4±1.1196.9±1.20.004
 24-h Urine Na+ (mEq/d)<0.001
  8th–16th 24-h Na reduction<25% (n=60)147.5±6.1162.8±5.5<0.001
  8th–16th 24-h Na reduction>25% (n=58)177.7±9.8104.9±9.0<0.001
 Systolic BP (mmHg)0.76
  8th–16th 24-h Na reduction<25% (n=60)123.2±1.5122.5±1.40.68
  8th–16th 24-h Na reduction>25% (n=58)122.1±2.4122.4±2.30.91
 Diastolic BP (mmHg)0.28
  8th–16th 24-h Na reduction<25% (n=60)73.3±1.074.8±1.10.16
  8th–16th 24-h Na reduction>25% (n=58)75.9±1.675.1±1.70.68
  • Data are expressed by least squares means±SEMs from a linear mixed effects model.

  • a P value was from the result of a logarithm-transformed variable because of skewed distribution of albumin excretion.