Table 2.

Association of kidney function and CKD risk factors with glomerular volume and profile tubular area

CharacteristicMean Glomerular VolumeMean Profile Tubular Area
UnadjustedMultivariable AdjustedUnadjustedMultivariable Adjusted
Percent DifferenceP 
ValuePercent DifferenceP 
ValuePercent DifferenceP 
ValuePercent DifferenceP 
Value
Age per 10 yr−1.10.180.06 0.951.00.172.4 0.01
Men15.8<0.0017.3 0.0046.9 <0.0014.9 0.03
24-h Urine protein excretiona1.6 0.130.0050.99
Log 24-h urine albumin excretion, per doubling3.2 <0.0011.80.012.9 <0.0012.4 <0.001
Measured GFR (ml/min)a7.7<0.0014.4 <0.001
Measured GFR (ml/min per 1.73 m)2a1.50.152.00.091.9 0.033.1 0.002
18-h Overall SBPa5.5 <0.0012.3 0.01
18-h Overall DBPa3.5 <0.0011.10.20
Hypertension8.5 0.013.6 0.297.9 0.013.4 0.27
Family history of ESRD9.5<0.0017.3 0.014.4 0.014.3 0.02
Triglyceridesa4.1<0.0011.8 0.03
HDL cholesterola−5.4<0.001−3.0<0.001
LDL cholesterola1.6 0.120.8 0.36
Glucosea6.2<0.0011.7 0.05
Uric acida9.0<0.0013.6 0.012.9 <0.0010.15 0.90
BMIa10.7<0.0018.2 <0.0014.9 <0.0014.2 <0.001
Metabolic syndrome17.8<0.0017.0 0.01
  • SBP, systolic BP; DBP, diastolic BP.

  • a Per SD.