Table 1.

Institute of Medicine Standards for Clinical Practice guidelinesa

Clinical practice guidelines should be on the basis of a systematic review of the existing evidence
Be developed by a knowledgeable multidisciplinary panel of experts and representatives from key affected groups
Consider important patient subgroups and patient preferences as appropriate
Be on the basis of an explicit and transparent process that minimizes distortions, biases, and conflicts of interest
Provide a clear explanation of the logical relationships between alternative care options and health outcomes
Provide ratings of both the quality of evidence and the strength of the recommendations
Be reconsidered and revised as appropriate when important new evidence warrants modifications of recommendations
  • a See ref. 12.