Table 2.

Association between MeDi score and incident eGFR<60 ml/min per 1.73 m2

MeDi ScoreOR 
(95% CI)P 
Value
Continuous (per 1-point increase in MeDi score)
 Unadjusted0.81 (0.72 to 0.92)0.002
 Demographic adjusteda0.83 (0.73 to 0.95)<0.01
 Fully adjustedb0.83 (0.71 to 0.96)0.02
MeDi score ≥5 (versus <5)
 Unadjusted0.49 (0.33 to 0.75)0.001
 Demographic adjusteda0.49 (0.32 to 0.75)0.001
 Fully adjustedb0.50 (0.31 to 0.81)0.004
MeDi quartiles (unadjusted)
 0–3Ref
 41.30 (0.78 to 2.16)0.31
 50.52 (0.28 to 0.95)0.03
 6–90.60 (0.34 to 1.07)0.08
MeDi quartiles (demographic adjusted)
 0–3Ref
 41.44 (0.85 to 2.46)0.18
 50.50 (0.27 to 0.93)0.03
 6–90.67 (0.37 to 1.21)0.18
MeDi quartiles (fully adjusted)
 0–3Ref
 41.61 (0.88 to 2.97)0.12
 50.51 (0.26 to 1.02)0.06
 6–90.76 (0.39 to 1.46)0.41
  • OR, odds ratio; 95% CI, 95% confidence interval.

  • a Adjusted for age (years), sex, race (black, white, Hispanic, or other), education (high school completion versus not), and insurance status (Medicare/private insurance versus Medicaid/no insurance).

  • b Adjusted for age (years), sex, race/ethnicity (black, white, Hispanic, or other), education (high school completion versus not), insurance status (Medicare/private insurance versus Medicaid/no insurance), physical activity (any exercise versus not), BMI (kg/m2), diabetes (yes or no), smoking status (never, past, or current), hypertension (yes or no), LDL (mg/dl), HDL (mg/dl), baseline eGFR (ml/min per 1.73 m2), and ACE inhibitor/ARB usage (yes or no).