Table 2.

Renal biopsy findings

Renal Biopsy FindingsNumber of Patients (%)P Value
All PatientsTertile 1 (Low)Tertile 2 (Medium)Tertile 3 (High)Tertile 1 Versus 2Tertile 1 Versus 3Tertile 2 Versus 3
Interstitial fibrosis, %
 Minor82 (69)32 (80)28 (72)22 (56)0.860.380.59
 Moderate23 (19)2 (5)9 (23)12 (31)0.060.020.63
 Extended13 (11)6 (15)2 (5)5 (13)0.27>0.990.44
Glomerular lesions (electron microscopy), %
 I9 (8)4 (10)2 (5)3 (8)0.68>0.99>0.99
 II73 (62)21 (53)28 (72)24 (62)0.470.710.72
 III22 (19)8 (20)6 (15)8 (21)0.77>0.990.77
 IV14 (12)7 (18)3 (8)4 (10)0.320.53>0.99
Nephrosclerosis, %
 No67 (57)29 (73)23 (59)15 (38)0.600.130.33
 Yes51 (43)11 (27)16 (41)24 (62)0.500.070.34
 Minor23 (19)4 (10)9 (23)10 (26)0.240.16>0.99
 Moderate24 (20)6 (15)5 (13)13 (33)>0.990.200.12
 Severe4 (3)1 (3)2 (5)1 (3)>0.99>0.99>0.99
Scarred glomeruli per biopsy specimen, %10±179±1510±1713±180.720.240.42
  • Interstitial fibrosis, glomerular lesions assessed by electron microscopy according to the classification by Ehrenreich and Churg (15), hypertensive glomerulosclerosis, and the percentage of scarred glomeruli per renal biopsy specimen are presented.