Table 3.

Association between MeDi score and upper quartile of eGFR decline

MeDi ScoreOR 
(95% CI)P 
Value
Continuous (per 1-point increase in MeDi score)
 Unadjusted0.88 (0.80 to 0.96)0.01
 Demographic adjusteda0.89 (0.80 to 0.98)0.02
 Fully adjustedb0.88 (0.79 to 0.98)0.02
MeDi score ≥5 (versus <5)
 Unadjusted0.65 (0.48 to 0.88)0.01
 Demographic adjusteda0.65 (0.47 to 0.88)0.01
 Fully adjustedb0.58 (0.41 to 0.83)0.003
MeDi quartiles (unadjusted)
 0–3Ref
 40.81 (0.53 to 1.23)0.32
 50.52 (0.33 to 0.82)0.004
 6–90.63 (0.41 to 0.95)0.03
MeDi quartiles (demographic adjusted)
 0–3Ref
 40.86 (0.55 to 1.33)0.49
 50.51 (0.32 to 0.81)0.004
 6–90.66 (0.43 to 1.02)0.06
MeDi quartiles (fully adjusted)
 0–3Ref
 41.01 (0.62 to 1.66)0.96
 50.49 (0.29 to 0.82)0.01
 6–90.67 (0.41 to 1.10)0.11
  • a Adjusted for age (years), sex, race/ethnicity (black, white, Hispanic, or other), education (high school completion versus not), and insurance status (Medicare/private insurance versus Medicaid/no insurance).

  • b Adjusted for age (years), sex, race/ethnicity (black, white, Hispanic, other), education (high school completion versus not), insurance status (Medicare/private insurance versus Medicaid/no insurance), physical activity (any exercise versus not), BMI (kg/m2), diabetes (yes or no), smoking status (never, past, or current), hypertension (yes or no), LDL (mg/dl), HDL (mg/dl), baseline eGFR (ml/min per 1.73 m2), and ACE inhibitor/ARB usage (yes or no).