Table 2.

Multilevel model analysis of the unadjusted and adjusted variations at the patient, facility, and geographic levels for the level of eGFR at dialysis initiation

ModelIntraclass Correlation (%)Variance EstimateSEMP Value
eGFR as a continuous variablea
 Unadjusted
  Patient90.717.60.14<0.001
  Facility6.61.30.28<0.001
  Geography2.70.50.420.11
 Fully adjusted
  Patient96.912.90.10<0.001
  Facility3.10.40.09<0.001
  Geography0.00.00.00>0.99
eGFR≥10.5 ml/min per 1.73 m2a
 Unadjusted
  Patient
  Facility8.20.30.07<0.001
  Geography2.60.10.090.26
 Fully adjusted
  Patient
  Facility4.50.20.04<0.001
  Geography0.10.00.020.40
eGFR as a continuous variable and predialysis care>90 db
 Unadjusted
  Patient88.216.00.15<0.001
  Facility8.71.60.34<0.001
  Geography3.10.60.480.12
 Fully adjusted
  Patient95.711.90.11<0.001
  Facility4.20.50.12<0.001
  Geography0.20.00.070.38
  • The patient-level intraclass correlation was not calculated for the binary outcome to avoid a fixed value assumption. The fully adjusted model included the following covariates: facility-level factors (percentage catheter use, transplantation facility, peritoneal dialysis facility, average hemoglobin and phosphate, average distance that a patient resided from the nearest dialysis center, and number of patients), patient case mix (age, sex, body mass index, race, comorbidities, distance to facility, length of predialysis care, peritoneal dialysis, serum phosphate, albumin, and hemoglobin), and year.

  • a Geographic regions, 12; facilities, 63; patients, 33,263. Median number of patients per facility=795 (interquartile range=532–1053).

  • b Geographic regions, 14; facilities, 63; patients, 23,902. Median number of patients per facility=795 (interquartile range=532–963).