Table 6.

Multivariable adjusted hazards ratios (95% confidence intervals) for hospitalization associated with number of nondisease-specific problems among REGARDS Study population ≥75 years old by albumin-to-creatinine ratio

No. of Nondisease-Specific ProblemsAlbumin-to-Creatinine Ratio, mg/g
<30 (n=1795)≥30 (n=473)
01 (reference)1 (reference)
11.25 (1.08 to 1.45)1.23 (0.93 to 1.62)
21.62 (1.34 to 1.96)1.62 (1.21 to 2.17)
3–61.75 (1.40 to 2.20)
P trend<0.0010.001
  • Restricted to 2268 REGARDS participants who were enrolled in Medicare parts A and B (fee-for-service hospital and outpatient coverage, respectively) but not Medicare Advantage at the time of their baseline study visit. Multivariable adjustment includes age, race, sex, education, income, region of residence, current cigarette smoking, atrial fibrillation, coronary heart disease, stroke, diabetes, systolic BP, diastolic BP, waist circumference, HDL cholesterol, total cholesterol, and C-reactive protein (log transformed). Because of the smaller sample size with Medicare data, we pooled those with ACR ≥ 30 mg/g and those with two or more nondisease-specific problems.