Table 3.

Logistic regression models for 90-day mortality among all patients with RRT and among patients with classic RRT

CovariateUnivariate Odds Ratio (95% CI)P ValueMultivariate Odds Ratio (95% CI)P Value
All patients on RRTa
 Age (5 yr)1.18 (1.07 to 1.30)0.0011.20 (1.06 to 1.36)0.01
 Number of preexisting chronic illnessesb1.03 (0.84 to 1.27)0.770.94 (0.72 to 1.23)0.66
 Study site0.150.90
 Source of admission0.180.54
 SAPS II score without age points1.07 (1.05 to 1.09)<0.0011.06 (1.04 to 1.09)<0.001
 Mechanical ventilation (ICU stay)3.65 (1.82 to 7.32)<0.0012.93 (1.23 to 6.96)0.02
 Vasoactive drugs (ICU stay)3.10 (1.29 to 7.41)0.011.30 (0.41 to 4.12)0.66
 Severe sepsis until day 51.99 (1.18 to 3.37)0.011.16 (0.61 to 2.24)0.58
 Time from ICU admission to RRT (h)1.00 (0.99 to 1.01)0.931.01 (0.98 to 1.02)0.17
 CRRT as initial modality0.50 (0.26 to 0.95)0.040.97 (0.42 to 2.21)0.94
 Classic RRT (versus pre-emptive RRT)2.25 (1.31 to 3.86)0.0032.05 (1.03 to 4.09)0.04
Patients on classic RRTc
 Age (5 yr)1.21 (1.03 to 1.41)0.021.32 (1.09 to 1.62)0.01
 Study site0.610.75
 SAPS II score without age points1.07 (1.04 to 1.10)<0.0011.08 (1.04 to 1.12)<0.001
 Mechanical ventilation (ICU stay)6.36 (2.79 to 14.49)<0.0014.14 (1.57 to 12.39)0.01
 Vasoactive drugs (ICU stay)2.30 (0.87 to 6.08)0.090.42 (0.09 to 1.76)0.40
 Severe sepsis until day 51.85 (0.93 to 3.68)0.081.19 (0.48 to 2.94)0.71
 CRRT as initial modality0.47 (0.20 to 1.06)0.070.96 (0.31 to 3.04)0.95
 Classic-delayed RRT (versus classic–urgent RRT)3.37 (1.57 to 7.22)0.0023.85 (1.48 to 10.22)0.01
  • CRRT, continuous RRT; 95 % CI, 95% confidence interval.

  • a Model included all 239 patients. Hosmer–Lemeshow test=9.82; P=0.28.

  • b In total, 10 of 239 (4.2%) patients with missing data were assumed to have no comorbidities.

  • c Model included all 134 patients. Hosmer–Lemeshow test=3.13; P=0.93.