Table 1.

Baseline characteristics of the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study population ≥75 years old by eGFR

Participant CharacteristicseGFR, ml/min per 1.73 m2
≥6045–59<45
n2616606335
Age, yr79.0±3.780.2±4.280.6±4.2
Women54.853.664.2
Black33.332.338.5
Less than a high school education15.520.121.5
Household income <$20,00021.120.530.5
Geographic region
 Stroke belt30.329.927.5
 Stroke buckle18.922.621.5
 Other region50.847.551.0
Current smoker5.26.07.2
Hypertension64.678.082.0
Atrial fibrillation12.315.125.0
Coronary heart disease25.035.435.9
Stroke7.510.410.6
Diabetes mellitus17.325.930.2
Systolic BP (mmHg)131.2±17.4131.9±18.0129.7±17.2
Diastolic BP (mmHg)74.5±9.473.4±9.871.5±10.0
Waist circumference (cm)92.9±14.994.4±13.795.0±13.4
HDL cholesterol (mg/dl)54.0±16.851.8±17.450.1±15.9
Total cholesterol (mg/dl)185.9±39.0181.7±39.4180.0±37.8
High-sensitivity C-reactive protein (mg/L)1.8 (0.9–4.2)2.0 (0.9–4.5)2.8 (1.3–6.1)
Cognitive impairment13.215.218.8
Depressive symptoms9.89.79.0
Exhaustion14.618.023.3
Falls (≥2 within the past year)9.38.910.8
Impaired mobility17.721.328.4
Polypharmacy (≥10 medications)19.827.634.6
  • Numbers are percentages or means±SDs except for high-sensitivity C-reactive protein, which is medians (25th–75th quartiles).