Table 4.

Characteristics of matched patients on pre-emptive RRT compared with matched patients who did not receive RRT

CharacteristicPre-emptive RRTNon-RRTP ValueSMD
Age (yr)64.0 [56.0–76.0]67.0 [55.0–75.0]0.92−0.5
Men44/67 (65.7)46//67 (68.7)0.03−6.4
CKD10/66 (14.9)7/67 (10.4)0.6113.6
Operative admission33/67 (49.3)28/67 (41.8)0.5215.1
Emergency admission56/67 (83.6)58/67 (86.6)0.79−8.4
Admitted froma0.92
 Operating room or recovery room32/67 (47.8)28/67 (41.8)
 Emergency room14/67 (20.9)21/67 (31.3)
 Ward15/67 (22.4)14/67 (20.9)
 Other6/67 (9.0)4/67 (6.0)
SAPS II score45.0 [35.0–59.0]41.0 [32.0–58.0]0.1113.5
SAPS II score without age and renal components24.0 [16.0–30.0]24.0 [17.0–30.0]0.83−0.4
SOFA score, first 24 h10.0 [8.0–13.0]9.0 [7.0–12.0]0.2416.9
SOFA score, maximum12.0 [9.0–14.0]9.0 [8.0–13.0]0.00152.6
Mechanical ventilation (ICU stay)58/67 (86.8)47/67 (70.1)0.0420.6
Severe sepsis until day 531/67 (46.3)29/67 (43.3)0.036.0
AKI before RRT or within days 1–555/67 (82.1)59/67 (88.1)0.13−16.9
Highest AKI stage before RRT or within 24 h of ICU admission (patients not on RRT)a0.35
 Stage 115/67 (22.4)15/67 (22.4)
 Stage 221/67 (31.3)23/67 (34.3)
 Stage 319/67 (28.4)20/67 (29.9)
Treatment restrictionsb16/66 (24.2)29/67 (43.3)0.02−41.2
At ICU admission
 Vasoactives57/67 (85.1)60/67 (89.6)0.61−13.6
 Severe sepsis28/67 (41.8)23/67 (34.3)0.4715.5
 Highest norepinehprine dose within first 24 h (μg/kg per minute)0.22 [0.06–0.44]0.18 [0.07–0.35]0.285.0
 Cumulative urine output within the first 24 h (ml)865 [460–1760]1135 [546–1720]0.780.9
 First creatinine (mg/dl)1.6 [1.2–2.2]1.4 [1.0–2.7]0.95−2.5
 First lactate (mmol/L)2.8 [1.5–5.8]2.5 [1.3–5.2]0.717.7
 Received diuretics35/64 (54.7)30/65 (46.2)0.3117.1
90-d mortality18/67 (26.9)33/67 (49.3)0.01−47.4
  • Data are expressed as median [interquartile range] or number/total number (percentage). SMD, standardized mean difference.

  • a Comparison across groups with marginal homogeneity test.

  • b Treatment restrictions include one or several of the following restrictions: (1) do not resuscitate, (2) do not increase the intensity of treatment, and (3) withdrawal of intensive care.