Table 7.

Multivariable adjusted hazards ratios (95% confidence intervals) for emergency department visits associated with number of nondisease-specific problems among the REGARDS Study population ≥75 years old by eGFR

No. of Nondisease-Specific ProblemseGFR, ml/min per 1.73 m2
≥60 (n=1648)<60 (n=620)
01 (reference)1 (reference)
11.11 (0.97 to 1.28)1.35 (1.07 to 1.70)
21.32 (1.09 to 1.60)1.30 (0.98 to 1.72)
3–61.61 (1.28 to 2.01)1.82 (1.31 to 2.54)
P trend<0.001<0.001
  • Restricted to 2268 REGARDS participants who were who were enrolled in Medicare parts A and B (fee-for-service hospital and outpatient coverage, respectively) but not Medicare Advantage at the time of their baseline study visit. Multivariable adjustment includes age, race, sex, education, income, region of residence, current cigarette smoking, atrial fibrillation, coronary heart disease, stroke, diabetes, systolic BP, diastolic BP, waist circumference, HDL cholesterol, total cholesterol, and C-reactive protein (log transformed). Because of the smaller sample size with Medicare data, we pooled participants with eGFR < 60 ml/min per 1.73 m2.