Table 4.

Multivariable Cox model of determinants of ESRD and all-cause death

VariablesESRD Hazard Ratio (95% Confidence Interval)All-Cause Death Hazard Ratio (95% Confidence Interval)
Age (1 yr)0.96 (0.96 to 0.97)a1.10 (1.10 to 1.11)a
Women0.49 (0.39 to 0.63)a0.60 (0.57 to 0.63)a
Body mass index≥30 kg/m2 (yes versus no)0.71 (0.50 to 1.01)1.02 (0.94 to 1.11)
Hypertension (yes versus no)1.60 (0.93 to 2.76)1.11 (1.02 to 1.21)a
Diabetes mellitus (yes versus no)1.63 (1.26 to 2.11)a1.61 (1.52 to 1.70)a
Coronary artery disease (yes versus no)1.33 (1.03 to 1.71)a1.48 (1.41 to 1.56)a
Dyslipidemia (yes versus no)1.11 (0.86 to 1.44)0.67 (0.64 to 0.71)a
Anemia (yes versus no)2.08 (1.50 to 2.89)a1.56 (1.44 to 1.69)a
Albuminuria (yes versus no)2.11 (1.57 to 2.84)a1.12 (1.01 to 1.24)a
Use of RAS inhibitors (yes versus no)1.17 (0.89 to 1.53)1.02 (0.97 to 1.08)
CKD stage
 1 and 2ReferenceReference
 3a1.44 (0.79 to 2.64)1.11 (0.99 to 1.23)
 3b11.04 (6.26 to 19.48)a1.66 (1.49 to 1.86)a
 491.2 (53.2 to 156.2)a2.75 (2.41 to 3.13)a
 5122.8 (67.9 to 222.0)a2.54 (2.01 to 3.22)a
  • Hazard ratios are adjusted for all variables included into the model. RAS, renin-angiotensin system.

  • a Significant hazard ratio.