Table 2.

Multivariable linear regression analyses showing the association of GFR and urine-to-plasma concentration ratio of urea with plasma copeptin (dependent variable) in 134 healthy kidney donors predonation and postdonation

DonorsModel 1Model 2Model 3
PredonationPostdonationPredonationPostdonationPredonationPostdonation
St. βP ValueSt. βP ValueSt. βP ValueSt. βP ValueSt. βP ValueSt. βP Value
GFR0.150.080.0080.930.020.84−0.080.410.020.85−0.160.87
 Age (yr)−0.25<0.01−0.130.18−0.27<0.01−0.110.26
 Men−0.180.04−0.35<0.001−0.140.10−0.32<0.001
 Plasma sodium0.030.730.030.44
 24-h urine volume−0.200.02−0.280.001
 MAP0.020.79−0.090.29
 Diuretics0.0030.980.030.73
U/P urea0.190.030.39<0.0010.080.400.290.001−0.090.410.120.35
 Age (yr)−0.24<0.01−0.010.86−0.310.001−0.070.48
 Men−0.160.07−0.270.002−0.160.08−0.300.001
 Plasma sodium0.020.780.060.45
 24-h urine volume−0.260.02−0.200.09
 MAP0.030.76−0.080.33
 Diuretics0.0060.940.020.79
  • MAP, mean arterial pressure; U/P urea, urine-to-plasma concentration ratio of urea.