Table 3.

Locus-wide nephrin gene sequence kernel association testing analysis weighted for rare variants

ModelP ValueQcMAF (%)N SNPs
Unadjusted2.95×10−8280,4170.2916
Admixture5.64×10−7159,0050.2815
Admixture and APOL1 G1/G21.18×10−6145,7540.2815
  • Q, test statistic (similar to chi-squared); cMAF, cumulative minor allele frequency for all SNPs analyzed; SNP, single-nucleotide polymorphism; APOL1, apolipoprotein L1 gene.