Table 2.

Renal histologic parameters in patients and control groups

Histologic ParameterPE (n=11)PC (n=25)HC (n=14)NPC (n=13)P Value
Acute tubular necrosis0 (0)4 (16)3 (21)3 (23)0.41
Congestion0 (0)0 (0)0 (0)3 (23)0.01
Endotheliosis6 (55)3 (12)2 (14)0 (0)0.003
 <20% of the lumen1 (17)3 (100)1 (50)NA
 20%–80% of the lumen3 (50)01 (50)NA
 >80% of the lumen2 (33)00NA
FSGS1 (9)2 (8)5 (36)0 (0)0.03
Global sclerosis>1%1 (9)0 (0)5 (36)1 (8)0.04
Glomerulitis0 (0)6 (24)1 (7)2 (15)0.23
Hyalinosis1 (9)4 (16)7 (50)10 (77)<0.001
Interstitial fibrosis tubular atrophy0 (0)0 (0)2 (14)0 (0)0.06
Intima fibrosis2 (18)7 (28)11 (79)5 (39)0.01
Ischemia0 (0)1 (4)3 (21)1 (8)0.17
Mesangium changes1 (9)0 (0)4 (29)1 (8)0.04
Microthrombi1 (9)0 (0)1 (7)0 (0)0.20
Edema1 (9)0 (0)0 (0)1 (8)0.34
Podocyte changes2 (18)0 (0)0 (0)0 (0)0.02
Tram tracking4 (36)0 (0)0 (0)0 (0)<0.001
  • Values are expressed as n (%). All patients with FSGS were classified as the “not otherwise specified” variant.