Table 3.

Factors independently associated with AKI after adjustment for confounders (stepwise logistic regression)

VariableOR (95% CI)P Value
Respiratory statusa
 No MV (reference)
 MV, no ARDS4.34 (3.71 to 5.10)<0.001
 ARDS11.01 (6.83 to 17.73)<0.001
Age (per yr)1.04 (1.03 to 1.04)<0.001
Chronic cardiac dysfunctionb1.54 (1.30 to 1.82)<0.001
Chronic liver diseaseb1.41 (1.14 to 1.76)<0.001
Immunodeficiencyb1.68 (1.45 to 1.76)0.002
Shock4.23 (3.38 to 5.29)<0.001
Diabetes mellitus1.62 (1.38 to 1.90)<0.001
Multiple myeloma1.91 (1.01 to 3.61)<0.001
  • Hosmer–Lemeshow statistics were as follows: κ2=11.8; P=0.16; C statistic: 0.77. OR, odds ratio; 95% CI, 95% confidence interval; MV, mechanical ventilation.

  • a Respiratory status was inserted as the dummy variable.

  • b Underlying comorbidities (chronic liver disease, chronic cardiac dysfunction, or immunodeficiency) were defined according to the Knaus definition (40).