Table 2.

Characteristics of the study groups at the final visit (n=91)

VariablePravastatin (n=49)Placebo (n=42)P Value
Age (yr)19±418±40.55
Height (cm)171±11170±110.73
Weight (kg)74±2068±200.20
Urine microalbumin excretion (μg/min)
 Mean29±3949±990.21
 Median14 [9, 32]14 [8, 31]0.81
Left ventricular mass index (g/m2)60±1558±130.69
Total kidney volume (ml)
 Mean739±433756±4260.85
 Median604 [428, 878]622 [479, 907]0.67
 Percent change (per 3 yr)27±1838±250.04
Total kidney volume corrected for height (ml/m)
 Mean429±244442±2440.80
 Median344 [251, 496]372 [271, 514]0.56
 Percent change (per 3 yr)21±1630±200.02
Serum creatinine (mg/dl)
 Mean0.8±0.20.7±0.10.29
 Median0.7 [0.7, 0.8]0.7 [0.6, 0.8]0.26
24-h urine creatinine clearance (ml/min per 1.73 m2)126±24126±250.98
BP (mmHg)
 Systolic123±10123±90.96
 Diastolic 74±975±80.59
Hematocrit (%)42±440±70.17
24-h urine protein (g/d)
 Mean0.2±0.10.2±0.20.38
 Median0.12 [0.09, 0.17]0.14 [0.09, 0.19]0.58
Cholesterol (mg/dl)
 HDL48±1649±100.92
 LDL71±2587±250.003
 Total141±32156±290.02
  • Values are the mean±SD or median [25th percentile, 75th percentile]. Non-normally distributed variables were also tested with the Wilcoxon rank sum test.