Table 2.

Median (interquartile range) concentrations of BNP-32 and NT-BNP-76 at baseline (first sample) and 5–6 months later (second sample) and median difference between the two by treatment group

VariableCKD 3–4 Dialysis Transplant
BNP-32 (pg/ml)n=48n=102n=73
 First sample102 (48–252)218 (93–445)66 (41–148)
 Second sample103 (34–269)280 (116–668)61 (31–161)
ΔBNP-32−9 (−47 to 39)13 (−66 to 171)−4 (−20 to 19)
NT-BNP-76 (pg/ml)n=49n=102n=71
 First sample698 (283 to 2,922)3850 (1776–12,323)379 (141–875)
 Second sample2529 (347–9277)a18,830 (6114– 61,009)b347 (144–981)
ΔNT-BNP-76778 (−57 to 7468)13,772 (2058–41,244)2 (−74 to 105)
  • BNP-32, 32–amino acid BNP; BNP, B-type natriuretic peptide; ΔBNP, change between first and second samples.

  • a P=0.004 compared with the first sample.

  • b P<0.001 compared with the first sample.