Table 1.

Baseline characteristics of the patients who had two measurements of NT-BNP-76 by treatment group

CharacteristicCKD 3–4 (n=49)Dialysis (n=102)Transplant (n=71)P Value
Age (yr)67.1±11.262.6±14.352.8±10.7<0.001
Men37 (76)60 (59)46 (63)0.13
Diabetes21 (43)20 (20)8 (11)<0.001
Cardiovascular disease19 (39)32 (31)9 (13)0.003
Coronary artery disease15 (31)24 (24)4 (6)0.001
Heart failure8 (16)19 (19)1 (1)0.002
Cerebrovascular disease1 (2)7 (7)2 (3)0.29
Peripheral vascular disease8 (16)16 (16)3 (4)0.05
Smoking30 (61)55(54)36 (51)0.52
Systolic BP (mmHg)132±21145±24129±14<0.001
Diastolic BP (mmHg)76±978±1377±60.46
BMI (kg/m2)27.3 (24.2–31.8)24.2 (21.8–27.4)26.5 (23.3–29.8)<0.001
Antiplatelet agent24 (49)39 (38)15 (21)<0.01
RAS blockade33 (67)39 (38)41 (58)0.001
Statin26 (53)46 (45)44 (62)0.09
β-Blocker17 (35)35 (34)35 (49)0.11
eGFR (ml/min per 1.73 m2)24±1135±16<0.001
Hemoglobin (g/dl)12.3±1.612.1±1.212.9±1.90.003
C-reactive protein (mg/L)3.8 (1.8–7.6)5.0 (3.0–11.8)1.6 (0.6–4.6)<0.001
Albumin (g/dl)4.01±0.393.76±0.414.12±0.32<0.001
cTnT-positive (sample 1)9 (19)48 (47)6 (8)<0.001
cTnT-positive (sample 2)10 (21)59 (58)8 (11)<0.001
  • Results are similar for patients with two measurements of 32–amino acid BNP (data not shown). Values expressed with a plus/minus sign are the mean±SD; all other values are the number (percentage) of patients. NT-BNP-76, N-terminal end B-type natriuretic peptide; BMI, body mass index; RAS, renin-angiotensin system; cTnT-positive, cardiac troponin T≥0.04 ng/ml.