Table 2.

Cox regression survival analysis for all-cause mortality at 14 months

VariableHazard Ratio (95% CI)P Value
Congestive heart failure0.80 (0.63 to 1.01)0.06
Lung disease0.81 (0.64 to 1.03)0.84
Liver disease1.08 (0.70 to 1.67)0.72
Ischemic heart disease1.12 (0.95 to 1.50)0.13
Peripheral vascular disease0.87 (0.53 to 1.42)0.57
Cancer (within 5 yr)0.97 (0.77 to 1.24)0.82
Hypertension0.80 (0.65 to 0.99)0.04
Dementia1.07 (0.76 to 1.52)0.67
Diabetes0.85 (0.67 to 1.07)0.16
Cerebrovascular disease0.99 (0.74 to 1.32)0.93
Connective tissue disease0.69 (0.42 to 1.12)0.13
Age1.00 (1.00 to 1.01)0.32
Preexisting CKD0.92 (0.76 to 1.13)0.42
Admission to ICU1.68 (1.18 to 2.39)0.01
Length of stay0.98 (0.98 to 0.99)<0.001
AKI stage 3 compared with AKI stages 1 and 21.25 (1.01 to 1.55)0.04
HA-AKI compared with CA-AKI1.75 (1.44 to 2.13)<0.001
  • Cox regression analysis was used to determine the influence of age (hazard per increasing year), length of stay (hazard per inpatient day), AKI severity (stage 3 compared with stages 1 and 2), and comorbidity on risk of death within 14 months after discharge. Listed comorbid conditions obtained from electronic records coding and defined as binary variables (present or absent). The hazard ratio of mortality in HA-AKI versus CA-AKI is shown at the bottom of the table (hazard ratio, 1.75; 95% CI, 1.44 to 2.13). 95% CI, 95% confidence interval; ICU, intensive care unit; HA-AKI, hospital-acquired AKI; CA-AKI, community-acquired AKI.