Table 2.

Individual absolute urinary oxalate levels and response depending on administered dosage during study weeks 0–24

PatientUox Level per Vitamin B6 Dosage (mmol/1.73 m2 per day)Genotype
Baseline (Vitamin B6, 0 mg/kg per day)Study Week 6 (Vitamin B6, 5 mg/kg per day)Study Week 12 (Vitamin B6, 10 mg/kg per day)Study Week 18 (Vitamin B6, 15 mg/kg per day)Study Week 24 (Vitamin B6, 20 mg/kg per day)
Uox ResponseUoxResponseUoxResponseUoxResponse
012.051.20+1.25+0.95+1.05+c.508G>A; c.959_960delCA
021.701.302.02.251.25c.508G>A; c.959_960delCA
032.351.25+1.45+1.20+1.95c.508G>A; c.364C>T
042.102.602.152.852.4c.33delC; c.33delC
051.901.20+1.351.501.8c.454T>A; c.1151T>C
061.651.05+0.68+1.00+0.9+c.508G>A; c.508G>A
072.250.75+1.00+1.20+1.00+c.508G>A; c.508G>A
083.502.802.752.25+1.65+c.327delG; c.327delG
092.311.20+1.30+1.60+1.35+c.560C>T; c.836T>C
102.302.802.602.852.75c.482G>A; c.976 del G
111.451.051.00+0.85+1.35c.508G>A; c.847-3C>G
121.501.02+0.60+1.050.90+c.508G>A; c.508G>A
  • Uox, urinary oxalate.