Table 4.

Performance of the RAI and serum biomarkers for prediction of subsequent severe AKI

TestRAINGALMMP-8Ela-2
Sensitivity93 (76 to 99)90 (72 to 97)86 (69 to 95)90 (73 to 97)
Specificity36 (33 to 37)34 (28 to 42)33 (30 to 34)44 (42 to 46)
PPV18 (15 to 19)18 (12 to 25)16 (13 to 18)20 (16 to 21)
NPV97 (90 to 99)97 (87 to 99)94 (87 to 98)97 (91 to 99)
AUC-ROC0.80 (0.75 to 0.86)0.72 (0.63 to 0.82)0.68 (0.59 to 0.78)0.72 (0.62 to 0.82)
  • Data are presented as the percentage (95% confidence interval). A RAI score of ≥8 is considered fulfillment of renal angina. The fulfillment of renal angina on day 0 was compared with the presence of AKI on day 3 of admission for the sensitivity, specificity, PPV, and NPV. The absolute value of the RAI (range, 1–40) was used to derive the AUC-ROC.