Table 1.

Baseline characteristics

CharacteristicAllElderly (≥75 yr)Nonelderly (18–74 yr)P Value
N (%)46490 (19)374 (81)
Age (yr), mean (SD)59.9 (15.7)81.3 (4.9)54.8 (12.3)
Men, n (%)237 (51.0)44 (48.8)193 (51.6)0.64
Ancestry, n (%)
 European American230 (49.6)66 (73.3)164 (43.8)<0.001
 African American218 (47.0)24 (26.7)194 (51.9)
 Hispanic16 (3.4)016 (4.3)
HD vintage (d)
 Mean (SD)629 (1180)547 (1063)649 (1207)0.47
 Median (25th, 75th percentiles)21 (21, 777)21 (21, 812)21 (21, 774)
Cause of end stage kidney disease, n (%)
 Diabetes167 (36.0)32 (35.6)135 (36.1)0.92
 GN65 (14.0)4 (4.4)61 (16.3)0.004
 Hypertension-attributed70 (15.1)15 (16.7)55 (14.7)0.64
 AKI30 (6.5)9 (10)21 (5.6)0.13
 Autosomal dominant polycystic kidney disease8 (1.7)08 (2.1)0.16
 Paraproteinemia13 (2.8)1 (1.1)12 (3.2)0.28
Comorbidities, n (%)
 Coronary artery disease147 (31.7)46 (51.1)101 (27.0)<0.001
 Diabetes mellitus260 (56.0)52 (57.8)208 (55.6)0.71
 Congestive heart failure143 (30.8)44 (48.9)99 (26.5)<0.001
 Hypertension434 (93.5)85 (94.4)349 (93.3)0.69
 Peripheral vascular disease73 (15.7)18 (20.0)55 (14.7)0.22
Medications, n (%)
 Immunosuppressant26 (5.6)1 (1.1)25 (6.6)0.05
  • Age is expressed in years at study entry. Immunosuppressant medications included prednisone, cyclosporine, tacrolimus, sirolimus, mycophenolate mofetil, azathioprine, methotrexate, or chemotherapy.