Table 1.

Baseline characteristics by quartiles of FGF-23

CharacteristicFibroblast Growth Factor-23 Quartile
1234
Range (RU/ml)<5454–7071–100>100
Participants (n)824821807789
Demographics
 Age (yr)77±578±578±579±5
 Women53576467
 African American23151214
Prevalent disease
 History of stroke5758
 History of heart failure35721
 History of coronary heart disease19202534
Cardiovascular risk factors
 Hypertension57616369
 Diabetes15202329
 Current smoker561010
 Body mass index (kg/m2)26.3±4.326.6±4.227.3±4.627.6±5.3
 Total cholesterol (mg/dl)200±37202±38203±41203±42
 Albumin (g/dl)3.84±0.303.85±0.303.82±0.293.81±0.31
 C-reactive protein (mg/L)1.90 (0.91, 3.92)2.21 (0.99, 4.68)2.87 (1.28, 5.82)3.14 (1.51, 6.74)
Kidney function
 eGFRCrCyC (ml/min per 1.73 m2)77±1471±1566±1556±19
 UACR (mg/g)6.95 (4.29, 14.42)8.43 (4.52, 17.20)8.33 (4.72, 18.99)13.55 (6.15, 55.12)
  • Data are presented as the mean ± SD, median (interquartile range), or percentage. FGF-23, fibroblast growth factor-23; eGFRCrCyC, creatinine-cystatin C estimated GFR; UACR, urine albumin-to-creatinine ratio.