Table 1.

Patient characteristics

Clinical DataNo CKDNew CKDP ValueNonprogressive CKDProgressive CKDP Value
N291278
Age ± SD (yr)31.3±9.034.3±11.70.3839.1±14.140.5±10.80.83
Mean follow-up (yr)5.8±1.26±1.80.685.3±0.955.6±1.60.42
Men (%)14000
African American (%)28500.281462.50.12
Class III or IV LN (%)45670.3143501.00
Initial SCr (mg/dl)0.85±0.150.75±0.150.061.94±0.832.15±0.810.63
Final SCr (mg/dl)0.83±0.121.78±1.95a<0.0011.56±0.874.0±2.45b0.009
Median time in flare (mo; range)c0 (0–28)20 (0–48)<0.0010 (0–22)15.5 (0–48)0.16
Median new RFs/yrc0 (0–1.4)0.56 (0–2)<0.0010 (0–0.5)0.33 (0–1)0.13
Median time in renal health (mo)c52 [(6–74)30.4 (0–50)0.00448 (14–75)25 (0–48)0.06
  • LN, lupus nephritis; SCr, serum creatinine; RFs, renal flares.

  • a P<0.005 for final versus initial SCr (new CKD group).

  • b P=0.02 for final versus initial SCr (progressive CKD group).

  • c Comparison by Wilcoxon test.