Table 1.

Baseline patient characteristics

Patient CharacteristicsTotal Cohort (N=714)Inflammation Cohort(n=405)a
Patient characteristics
 Age (yr)64.1±13.763.7±13.9
 Men445 (62)252 (62)
 Region
  The Netherlands597 (84)390 (96)
  Norway15 (2)15 (4)
  Canada102 (14)NA
 History of cardiovascular disease313 (44)177 (44)
 Diabetes mellitus170 (24)85 (21)
 Dialysis vintage (yr)2 (1–4)1.8 (0.9–3.4)
 Systolic BP (mmHg), predialysis147±21142±18
 Diastolic BP (mmHg), predialysis75±1273±11
 Body weight (kg), postdialysis72.4±14.471.7±14.6
 Body mass index (kg/m2), postdialysis 25.4±14.425.0±4.8
 Subjective global assessment classification
  Well nourished580 (81)345 (81)
  Mild-to-moderate malnutrition123 (17)71 (18)
  Severe malnutrition1 (0)1 (0)
 Residual kidney function (defined as urine  output>100 ml/24 h)376 (53)230 (57)
 Estimated GFR (ml/min per 1.73 m2)3.2 (1.3–5.5)2.6 (1.2–5.1)
Treatment characteristics
 Treatment frequency
  3×/wk668 (94)375 (93)
  2×/wk44 (6)30 (7)
 Duration of a dialysis session (min)226±23227±23
 Blood flow (ml/min)300 (300–348)300 (300–325)
 Dialysis access
  Fistula567 (80)339 (84)
  Graft100 (14)53 (13)
  Central venous catheter47 (6)10 (3)
 Single pool Kt/Vurea1.40±0.221.39±0.20
Laboratory parameters
 Hemoglobin (g/dl)11.8±1.2511.9±1.25
 Phosphorus (mg/dl)5.08±1.535.16±1.59
 Albumin (g/dl)b4.0±0.384.0±0.41
 Creatinine (mg/dl), predialysis9.74±2.899.80±2.83
 Cholesterol (mg/dl)142±37142±39
 High-sensitivity C-reactive protein (mg/L)NA3.93 (1.38–10.40)
 IL-6 (pg/ml)NA2.06 (1.21–3.82)
  • Data are presented as the mean±SD, n (%), or median (interquartile range). To convert albumin in g/dl to g/L, multiply by 10. NA, not applicable.

  • a Subpopulation of the 714 patients in which CRP and IL-6 measurements were done.

  • b Albumin concentrations measured with the bromcresol purple method were converted to bromcresol green concentrations.