Table 1.

Clinical characteristics of the patients

Patient CharacteristicsCKD GroupP Values
CKD2–3 (n=24)CKD4–5 (n=28)HD (n=25)CKD2–3 Versus CKD4–5Pre-HD Versus HD
Sex (men/women)14/1015/1320/50.730.04
Diabetes (yes/no)11/1315/1312/130.870.58
Age (yr)65.6±14.074.5±7.073.0±13.20.0080.19
eGFR (ml/min per 1.73 m2)51.6±16.919.9±6.5<0.001
Dialysis vintage (yr)3.1±3.5
Plasma concentrations
 Protein (g/dl)7.4±0.57.2±0.56.4±0.70.10<0.001
 Albumin (g/dl)4.1±0.33.7±0.43.2±0.4<0.001<0.001
 Hemoglobin (g/dl)13.9±1.412.8±1.711.2±1.90.02<0.001
 BUN (mg/dl)26.2±10.259.7±17.359.9±21.3<0.0010.004
 Uric acid (mg/dl)6.3±1.57.9±1.65.9±1.1<0.0010.21
 Creatinine (mg/dl)1.7±0.53.7±1.27.9±2.4<0.001<0.001
 Na+ (mEq/L)139.7±2.2139.7±3.1136.7±3.10.94<0.001
 HCO3 (mEq/L)26.9±2.824.2±3.523.7±3.10.0040.04
 PTH (pmol/L)5.3±3.127.7±25.433.7±24.6<0.001<0.001
 CRP (mg/L)2.8±2.59.3±21.131.4±81.20.01<0.001
Urinary protein to creatinine ratio (g/g)0.55±1.51.79±2.4<0.001
  • All values are mean ± SD unless stated otherwise. CKD2–3, CKD stages 2 and 3; CKD4–5, CKD stages 4 and 5; HD, hemodialysis; eGFR, estimated GFR; ND, not determined; PTH, parathyroid hormone; CRP, C-reactive protein.