Baseline characteristics and treatment regimen, organized by response category during adrenocorticotropic hormone therapy
| Variable | Steroid Response Category (n) | Age (yr) | Sex (n) | Race/Ethnicity (n) | FSGS Morphology (n) | Time from Diagnosis to Treatment (mo) | Previous IMD (n) | Creatinine (mg/dl) | eGFR (ml/min per m2) | Proteinuria (mg/d) | IMD use during ACTH (n) | Treatment Regimen (n) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Complete remission (n=2) | SR: 2 | 55 (40–69) | M: 1 F: 1 | WNH: 2 | Tip: 2 | 95 (94–96) | 2: 1 4: 1 | 0.9 (0.6–1.2) | 82 (71–93) | 3215 (2100–4330) | Yes: 0 No: 2 | Stanford (1) Columbia (1) |
| Partial remission(n=5) | SR: 3 SD: 2 | 43 (21–64) | M: 1 F: 4 | WNH: 3 BNH:1 BH: 1 | NOS: 2 Tip: 2 Cellular: 1 | 12 (2–56) | 1: 2 2: 1 3: 2 | 1.8 (1.1–3.6) | 49 (17–76) | 7849 (5046–15,200) | Yes: 2 No: 3 | Stanford (2) Columbia (1) Individual (2) |
| Failed (n=17) | SR: 9 SD: 5 NA: 3 | 44 (18–66) | M: 12 F: 5 | WNH: 8 BNH: 2 WH: 7 | NOS: 6 Tip: 7 Cellular: 3 Collapsing: 1 | 31 (2–132) | 0: 2 1: 3 2: 5 3: 4 4: 3 | 2.1 (0.6–3.4) | 49 (17–124) | 3170 (1600–23,800) | Yes: 2 No: 15 | Stanford (9) Columbia (5) Individual (3) |
Values with ranges in parentheses are medians and interquartile ranges. IMD, immunosuppressive therapy; ACTH, adrenocorticotropic hormone; SR, steroid resistant; SD, steroid dependent; M, male; F, female; WNH, white non-Hispanic; BNH: black non-Hispanic; BH, black Hispanic; NOS, not otherwise specified; WH: white Hispanic.