Table 1.

Baseline data for patients with FSGS treated with adrenocorticotropic hormone

PatientAge/(yr)/SexRace/EthnicityFSGS MorphologyPrevious ImmunosuppressionSteroid Response CategoryTime from Diagnosis to Treatment (mo)Serum Creatinine (mg/dl)eGFR (ml/min per 1.73 m2)Proteinuria (mg/g)
Columbia patients
 142/MaleWNHNOSSteroids, MMF, tacrolimusaSR2b2.7287000
 238/FemaleBNHNOSSteroids, MMF, cyclosporineSR562.3315046
 321/FemaleWNHTipSteroids, tacrolimus, cyclosporineSD121.1675200
 440/MaleWNHTipSteroids, tacrolimus, cyclosporine, MMFSR961.2712100
 518/MaleBNHTipSteroids, tacrolimus, MMFSR132.64211,200
 646/MaleWNHNOSSteroids, cyclophosphamide, MMF, tacrolimusSD303.22316,800
 764/FemaleWHCellularSteroids, MMF, tacrolimus,SD611.63510,300
 860/FemaleWNHCellularSteroids, tacrolimus, MMF, cyclosporineSR232.3232300
 966/MaleWNHTipSteroids, cyclosporine, MMFSR1321.0661600
 1036/MaleWNHNOSSteroids, cyclosporineSR960.81162200
 1130/FemaleWNHTipSteroids, MMF, cyclosporine, tacrolimusSR133.4178800
 1247/FemaleBHTipSteroids, tacrolimusaSR43.61715,200
Stanford patients
 1366/MaleWHNOSSteroidsSR142.2302020
 1465/MaleWNHCellularNoneNA82.7243170
 1564/MaleWNHNOSSteroidsSD221.04767240
 1627/MaleWHNOSSteroids, cyclosporineSR282.99352200
 1758/MaleWNHTipNoneNA42.2323550
 1829/MaleBNHCollapsingSteroids, MMFSR63.32823,800
 1928/FemaleWHTipCyclosporineNA190.61244860
 2040/MaleWHNOSSteroidsSD291.1842320
 2139/FemaleWHTipSteroids, MMFSR241.7371710
 2269/FemaleWNHTipSteroids, tacrolimusSR940.6934330
 2356/FemaleWNHCellularSteroidsSR21.1566560
 2439/MaleWHTipSteroids, cyclosporineSD291.0942000
  • eGFR, estimated GFR; WNH, white non-Hispanic; NOS, not otherwise specified; MMF, mycophenolate mofetil; SR, steroid resistant; BNH, black Non-Hispanic; SD, steroid dependent; WH, white Hispanic; BH, black Hispanic; NA, not applicable.

  • a Patients 1 and 12 also underwent plasma exchange therapy.

  • b Patient 1 had undergone four prior renal transplants for recurrent FSGS and was diagnosed with another recurrence 2 months before starting ACTH.