Table 5.

Adverse events observed during adrenocorticotropic hormone therapy

Steroid-like Adverse EventsEvents (n)Patients Experiencing Event (n)
 Swelling/edema/volume overload/weight gain55
 Increased energy44
 Mood alteration/anxiety/increased energy44
 Elevated BP33
 Acne22
 Dyspepsia/bloating22
 Increased appetite11
 Face swelling11
 Hyperglycemia/diabetes (reversible)11
Other reported adverse events
 Sinus congestion/rhinorrhea/upper respiratory tract symptoms44
 Muscle cramps44
 AKI21
 Pain/bruising at injection site22
 Tanning of skin22
 Rash22
 Fatigue11
 Vertigo11
 Pneumoniaa11
 Slow wound healing11
 Redness of face on injection days11
 Nausea11
 Headache11
 Polyuria11
 Palpitations11
 Intermittent chest discomfort11
 Loose stools11
 Shortness of breath after injection11
Total events (n)52
  • a Patient 6 was clinically diagnosed with pneumonia and treated empirically with azithromycin. No chest radiography was performed.