Table 2.

Multivariate linear regression analysis for correlates of plasma fibroblast growth factor 23 levels

VariableCoefficient for FGF23 (95% CI)P Value
eGFR (CKD-EPI)−0.32 (−0.41 to −0.23)<0.001
Ln copeptin0.26 (0.17 to 0.35)<0.001
Serum phosphate0.15 (0.07 to 0.23)<0.001
Hemoglobin−0.14 (−0.22 to −0.06)<0.001
Donor type (0=living; 1=deceased)−0.10 (−0.18 to −0.03)0.004
  • Excluded from the model: age, sex, history of one or more acute rejection episodes, cold ischemia time, waist circumference, cardiovascular history, systolic and diastolic BP, smoking status, diabetes mellitus, total cholesterol, proteinuria, 24-urinary phosphate and urea excretion, plasma 25(OH)-vitamin D, 1,25(OH)2 vitamin D, C-reactive protein, albumin, parathyroid hormone, use of angiotensin-converting enzyme inhibitor or angiotensin receptor blocker, use of active vitamin D, and total number of antihypertensive drugs. Coefficients are standardized β values. Model fit: R2=0.41. FGF23, fibroblast growth factor 23; CI, confidence interval; eGFR, estimated GFR; CKD-EPI, CKD-Epidemiology Collaboration; Ln; natural log.