Table 2.

Clinical and histopathological data at initial onset of 22 patients with ANCA-associated vasculitis whose urine samples were collected in remission stage

ParametersNumber
Number22
Men/women8/14
Average age (yr)62.5±14.9
Scr (mg/dl)
 Median (IQR)1.8 (1.0–2.6)
 Range0.6–9.8
eGFR (ml/min per 1.73 m2)
 Median (IQR)41.9 (24.3–77.1)
 Range5.7–120.3
ESR (mm/h)61.2±40.4
ANCA level (RU/ml)121.9±72.3
eGFR<60 ml/min per 1.73 m2 at diagnosis13 (59.1%)
Urinary protein (g/24 h)
 Median (IQR)0.8 (0.3–1.6)
 Range0–3.2
BVAS17.0±4.8
Average glomeruli per biopsy26.7±12.8
Glomerular lesions (%)
 Total crescents45.0±30.2
 Cellular crescents38.8±28.0
 Fibrous crescents median (IQR)0 (0–3.6)
Tubulointerstitial lesions
 Interstitial infiltration (−/+/++/+++)1/3/9/9
 Interstitial fibrosis (−/+/++)3/8/11
 Tubular atrophy (−/+/++)1/9/12
  • Scr, serum creatinine; IQR, interquartile range; eGFR, estimated GFR; ESR, erythrocyte sedimentation rate; BVAS, Birmingham Vasculitis Activity Scores.