Table 4.

Cox proportional hazards models for 24-hour urine phosphorus excretion with cardiovascular disease events

VariableUPE TertilesContinuous
Tertile 1 (<508 mg/d)Tertile 2 (508–748 mg/d)Tertile 3 (>748 mg/d)Per 300 mg/d Higher UPE (95% CI)P Value
Events/at risk (n/n)91/29468/29362/293221/880
Unadjusted: Hazard ratio (95% CI)1.00 (reference)0.67 (0.49 to 0.92)0.57 (0.42 to 0.79)0.76 (0.66 to 0.88)<0.001
Model 1: Hazard ratio (95% CI)1.00 (reference)0.77 (0.56 to 1.06)0.73 (0.52 to 1.03)0.84 (0.71 to 0.98)0.02
Model 2; Hazard ratio (95% CI)1.00 (reference)0.79 (0.57 to 1.09)0.70 (0.47 to 1.03)0.81 (0.68 to 0.97)0.02
  • Model 1; adjusted for age, sex, oral estrogen use (women), race, and estimated GFR. Model 2; adjusted for age, sex, oral estrogen use (women), race, estimated GFR, diabetes, hypertension, smoking, body mass index, cholesterol, HDL cholesterol, C-reactive protein, and urine calcium excretion. UPE, urinary phosphorus excretion; CI, confidence interval.