Table 2.

Baseline laboratory results by treatment allocation

Laboratory Parameter (Normal Range)PlaceboCholecalciferol
25(OH)D (adequacy ≥20–30 ng/ml)16±518±5
1,25(OH)2D (15–50 pg/ml)18±1018±5
iPTH (9–55 pg/ml)222±224335±327
ALP (30–115 U/L)116±57147±172
b-ALP (3.7–20.9 µg/L)16.7±9.022.1±19.9
TRAcP-5b (upper limits: 4.15, 4.82 U/L)4.50±2.065.00±2.35
Calcium (8.5–10.5 mg/dl)9.4±0.69.4±0.5
Phosphorus (2.5–5.8 mg/dl)4.8±1.65.4±1.6
Albumin (3.5–5.0 g/dl)3.9±0.43.8±0.4
C-reactive protein (≤10 mg/L)10 (5, 20)9 (5, 17)
Hemoglobin (11.5–18.0 g/dl)11.2±1.711.0±1.7
Ferritin (30–300 µg/L)348±200407±249
Transferrin saturation (11%–45%)24±930±15
  • n=30 for each group. Data are presented as mean ± SD or median (interquartile range). Multiply by 2.5 to convert 25(OH)D values to nmol/L; multiply by 2.4 to convert 1,25(OH)2D values to pmol/L; multiply by 0.11 to convert iPTH values to pmol/L; multiply by 0.25 to convert calcium values to mmol/L; and multiply by 0.32 to convert phosphorus values to mmol/L. 25(OH)D, 25-hydroxyvitamin D; iPTH, intact parathyroid hormone; ALP, alkaline phosphatase; b-ALP, bone-specific alkaline phosphatase; TRAcP-5b, tartrate-resistant acid phosphatase isoenzyme-5b (upper limits indicated for women and men, respectively).