Table 5.

Association of serum phosphorus concentrations with all-cause mortality and cardiovascular events

VariablePhosphorus Categories
<3.0 mg/dl3.0–3.4 mg/dl3.5–3.9 mg/dl4.0–4.4 mg/dl≥4.5 mg/dl
All-cause mortality
 Events/at risk (n/n)31/8197/244117/29967/18428/72
 Model 1:a HR (95% CI)1.00 (reference)1.14 (0.76 to 1.72)1.35 (0.91 to 2.02)1.49 (0.97 to 2.29)2.08 (1.22 to 3.52)
 Model 1 + eGFR: HR (95% CI)1.00 (reference)0.98 (0.65 to 1.47)1.22 (0.82 to 1.82)1.22 (0.79 to 1.89)1.43 (0.83 to 2.46)
Cardiovascular events
 Events/at risk (n/n)22/8170/24474/29935/18420/72
 Model 1:a HR (95% CI)1.00 (reference)1.12 (0.69 to 1.81)1.05 (0.65 to 1.70)0.92 (0.53 to 1.58)1.54 (0.82 to 2.89)
 Model 1 + eGFR: HR (95% CI)1.00 (reference)0.97 (0.60 to 1.57)0.95 (0.59 to 1.53)0.74 (0.43 to 1.28)1.01 (0.53 to 1.93)
  • HR, hazard ratio; CI, confidence interval; eGFR, estimated GFR.

  • a Adjusted for age, sex, estrogen use (women), and race.