Table 4.

Interaction of practitioner characteristics and report format with undocumented CKD

VariableOR for Undocumented CKD (95% CI): Adjusted OR from Models Stratified by Report FormataOR for Undocumented CKD (95% CI): Adjusted OR from Model with Interaction TermsbPb
SCr OnlyeGFRSCr OnlyeGFR
SexSex × format0.09
 Female (REF: male)3.79 (2.28, 6.29)2.15 (1.29, 3.56) Female (REF: male)3.74 (2.37, 5.92)2.27 (1.45, 3.56)
Experience (yr)Experience × format1.10 (0.60, 2.03)0.39 (0.19, 0.78)c0.03
 <20 (REF: 20+)0.94 (0.49, 1.80)0.34 (0.22, 0.54) <20 (REF: 20+)
Clinician trainingTraining × format0.03
 NP/PA (REF: MD/DO)2.16 (0.96, 4.87)0.80 (0.42, 1.54) NP/PA (REF: MD/DO)2.40 (1.08, 7.94)0.59 (0.30, 1.20)d
eGFR at inclusion (ml/min per 1.73 m2)eGFR at inclusion (ml/min per 1.73 m2)<0.01
 40–59 (REF: <30)10.58 (3.85, 29.04)9.26 (3.96, 21.64) 40–59 (REF: <30)9.77 (4.77, 20.0)
 30–44 (REF: <30)5.59 (2.63, 11.92)3.50 (1.93, 6.36) 30–44 (REF: <30)4.47 (2.61, 7.67)
ComorbidityComorbidity
 No DM (REF: DM)1.38 (0.94, 2.01)1.03 (0.68, 1.57) No DM (REF: DM)1.29 (1.01, 1.66)0.05
 No HTN (REF: HTN)2.45 (1.33, 4.53)1.29 (0.75, 2.22) No HTN (REF: HTN)1.52 (1.03, 2.25)0.04
Age (yr)Age (yr)0.02
 <60 (REF: 85+)0.68 (0.29, 1.59)0.80 (0.36, 1.78) <60 (REF: 85+)0.75 (0.40, 1.38)
 60–74 (REF: 85+)0.56 (0.30, 1.02)0.53 (0.30, 0.95) 60–74 (REF: 85+)0.55 (0.36, 0.84)
 75–84 (REF: 85+)0.86 (0.56, 1.32)1.26 (0.73, 2.17) 75–84 (REF: 85+)0.99 (0.72, 1.36)
  • OR, odds ratio; CI, confidence interval; SCr, serum creatinine; eGFR, estimated GFR; REF, reference category for OR; NP, nurse practitioner; PA, physician assistant; MD, doctor of medicine; DO, doctor of osteopathic medicine; DM, diabetes mellitus; HTN, hypertension.

  • a Variables included in the model: sex, eGFR at inclusion, age, laboratory report format, presence of DM, presence of HTN, and practitioner degree.

  • b Variables included in the model: sex, eGFR at inclusion, age, laboratory report format, presence of DM, presence of HTN, and practitioner degree. Interactions included in the model: laboratory report format × sex, laboratory report format × practitioner degree, and laboratory report format × clinician experience; P values are the significance levels for the factors and interaction terms.

  • c Differences between OR in SCr only and eGFR (P=0.03).

  • d Differences between OR in SCr only and eGFR (P=0.01).