Table 1.

Clinical characteristics of human participants from whom kidney tissue was examined

Kidney Donors
(n=15 Kidneys)PModerate ARAS
(n=12 Kidneys)PNephrectomy
(n=65 Kidneys)
Age (yr)61.4±8.40.1265.4±9.90.1763.9±10.8
Sex (female/male)7/80.485/70.3836/29
Creatinine (mg/dl)1.0±±±0.7
eGFR (ml/min per 1.73 m2)86.1±10.3<0.00158.2±23.90.0945.1±15.4
ACEI or ARB prescription (% of patients)0<0.0011000.0264.3
Statin prescription (% of patients)13.30.11400.5930
SBP (mmHg)124.6±13.80.004141.2±16.4<0.001177.9±26.4
DBP (mmHg)73.5±9.20.4671.2±7.9<0.00192.6±11.3
MAP (mmHg)90.5±10.10.1494.5±8.8<0.001121±13.9
Number of antihypertensive drugs0.4±0.8<0.0012.8±1.10.743.2±0.9
  • ARAS, atherosclerotic renal artery stenosis; BMI, body mass index; eGFR, estimated GFR using the Chronic Kidney Disease Epidemiology Collaboration equation; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; SBP, systolic BP; DBP, diastolic BP; MAP, mean arterial pressure.