Table 1.

Demographic variables, disease characteristics, and activity at diagnosis

Patients (n)3961
Male sex (%)5444
White (%)9586
Comorbid conditions (%)
 Ischemic heart disease1310
Admission at diagnosis (%)8290
Length of admission (d)a23 (15–35)20 (9–25)
Reason for consultation (%)
PR3-/MPO-ANCA (%)b54/4661/39
BVAS score6.9±3.18.2±3.8
EULAR categories (%)
 Early systemic57
Organs affected (%)
 Nervous system515
eGFR at diagnosis (mL/min per 1.73 m2)38±3549±43
Dialysis-dependent at diagnosis (n)2533
Alveolar hemorrhage (n)1010
Requiring intubation26
  • Values expressed with a plus/minus sign are the mean ± SD. There were no significant differences between the two cohorts except for a higher prevalence of rheumatologic manifestations in the CHUM cohort. HSCM, Hôpital du Sacré-Coeur de Montréal; CHUM, Centre Hospitalier de l’Université de Montréal; ENT, ear, nose, and throat; BVAS, Birmingham vasculitis activity score; EULAR, European League Against Rheumatism.

  • a Median (interquartile range).

  • b Five patients presented double-ANCA positivity, with PR3-ANCA being dominant in two cases.