Table 2.

Selected drugs associated with acute interstitial nephritis

Antibiotics
β-lactam drugsa
  Fluoroquinolonesa
  Rifampina
  Sulfa-based drugsa
  Erythromycin
  Chloramphenicol
  Vancomycin
  Minocycline
  Ethambutol
Analgesics
  Nonsteroidal anti-inflammatory drugsa
  Selective cyclooxygenase-2 inhibitors
Antiviral medications
  Acyclovir
  Abacavir
  Indinavir
  Atazanavir
Gastrointestinal medications
  Proton-pump inhibitorsa
  Histamine-2 receptor blockers
Anticonvulsants
  Phenobarbital
  Phenytoina
  Carbamazepine
Other
  Allopurinola
  5-Aminosalicylatesa
  Antiangiogenesis drugs (tyrosine kinase inhibitors)
  Diuretics
  Captopril
  IFN
  Cyclosporine
  • a Most common offending agents.